Best Hangover Remedy Pills & Hangover Prevention Supplements

Everyone likes to spend their time outdoors relaxing, meeting with friends, partying, and having fun, sometimes too much fun. No one wants to wake up the day after with a headache or experience nausea from being hungover. But there is help available, hangover supplements. There are multiple all-natural hangover prevention and relief supplements available on the market today.

But how do you decide which hangover supplement will provide relief and at a price that’s affordable? Don’t worry; we got you covered. This guide is to help differentiate high-quality hangover relief supplements from lower-quality products. This extensive guide will help consumers choose a hangover relief product, what the product provides in the way of relief, or if it’s a good price value or a packaged fabrication that claims to provide relief from hangover symptoms.

With our extensive research and review of the best hangover supplements, you can rest at ease and forget about your headache and consider hangovers a thing of the past with these hangover supplements. Many of the hangover supplements in this guide should be taken before going out to prevent hangovers or during a hangover to ease the morning-after symptoms.

What exactly do hangover supplements contain that make them so efficient? They blend vitamins, minerals and herbal extracts, and other natural ingredients that help protect, soothe and provide relief or prevention from hangovers.

Some hangover supplements help replenish B vitamins inside your body to prevent headaches and dehydration, while others contain herbal extracts to support the functioning of your liver. Some hangover supplements can help you to deal with alcohol hangovers. And some good-for-all kinds of hangovers are recommended to cure almost any type of hangover without putting a full stop to your partying spirit.

Now that we have done our research, we can proudly call ourselves ‘experts’ at preventing hangovers. After spending hours deliberating and privately testing, our editorial team has developed the following rankings for the Best Hangover Supplements available in the market today.

The Best Hangover Supplements for 2021

We read through several lab reports and contacted hangover supplement manufacturers. We went on to try and test these formulas ourselves. After much requisite research, we are here with the best hangover supplements that are available today. These are:

  • AfterDrink
  • Flyby
  • MoreLabs Morning Recovery
  • Drinkwel
  • PureWine
  • DrinkAde
  • Cheers
  • Over EZ
  • Blowfish
  • The Plug
  • Zaca
  • NoDaysWasted DHM Detox Recovery Blend
  • Toast
  • LiquidIV Energy Multiplier
  • Purple Tree
  • Sobur Hangover Support
  • Fewer Regrets



AfterDrink is a food supplements company that uses vitamins, antioxidants, and herbal extracts to make your mornings smooth and headache-free; for your after-party and weekend adventures, it’s your perfect weekend companion, which comes packaged as a convenient and transparent capsule. This hangover supplement is an ideal choice for anyone looking to cure their hangovers. According to the manufacturers of AfterDrink, this hangover supplement will restore and replenish your body entirely and support your mental performance, liver function, and normal metabolism.

AfterDrink uses only natural ingredients without any fillers to make its supplements; it is prevalent for other hangover supplements to use unusual plant-based and herbal extracts. AfterDrink is popularly known for using plant-based extracts with maximum antioxidant properties; this means that people consuming this supplement naturally feel the antioxidants supporting normal inflammation throughout their body. It would further help them recover from terrible headaches after a heavy night of drinking as the supplement is easy on your body.

Some of the key ingredients used in AfterDrink formulas are Ginger, DHM, and milk thistle. And the supplement is priced at just $35 per bottle. It is one of our most recommended and top-rated hangover pill supplements brands on our list.



Flyby is another popular hangover supplements brand on our list that offers a range of formulas targeting recovery, fuel, and overall stamina, along with promoting general health and wellness in your body. Within the hangover pill community, Flyby is best-known for its Recovery capsules. The Recovery supplement by Flyby costs about $35 per bottle, and this hangover pill utilizes natural ingredients to help you overcome hangover blues. Each bottle of Flyby comes packaged with a total of 90 capsules, thereby giving your body the required stamina and power to go through the day smoothly. As a customer, you look for natural and organic ingredients in any products that you buy. Hangover supplements are no exception which is why we think you should consider trying Flyby’s hangover Recovery capsules.

Flyby Recovery uses several herbal ingredients and is plant-based to support better liver function, reduce post-drinking drag, and replenish vital nutrients in your body for a more extended period. This hangover formula is science-backed and contains B vitamins (including B1, B2, B6, B9, B12), amino acids, DHM, milk thistle, prickly pear, among other natural ingredients.

Conceivably, one of the most commendable features of this hangover supplements company that we adore is that they are one of the only hangover brands on our list that runs its products on a clinical trial. To prove that their hangover supplement was efficient, Flyby used approximately 50 healthy subjects and placed them in a double-blind, randomized, and placebo-controlled setting to verify the functionality of its supplements.

MoreLabs Morning Recovery


The next brand on our list is MoreLabs that offers a variety of health and wellness supplements. Among all the wellness products that the company manufactures, MoreLabs Morning Recovery Formula is incredibly popular among its users. This particular solution called Morning Recovery is uniquely unique because it contains a proper blend of electrolytes that help to evoke the feeling of freshness and feel-good energy within your system the following day and leaving you hydrated. According to the company, we highly recommend taking at least one sip of this formula before consuming any drink. This Morning Recovery formula is perfectly compatible with wine, beers, spirits, and cocktails to help you block any aftereffects of drinking, especially hangovers. The Morning Recovery solution will help to energize your mornings. It will strengthen your mind and body to go through your day productively.

This genteel Morning Recovery formula utilizes a blend of adaptogens, herbs, vitamins, and minerals to help you feel better. And much similar to other hangover supplements companies mentioned on our list of Best Hangover supplements, MoreLabs guarantees that their hangover supplement will make you feel better, or else they will return your money. MoreLabs Morning Recovery has an average rating of about 4.9 stars out of 5 and has garnered hundreds of positive reviews from happy customers over the years. If you’re making a decision, then we are here to help as MoreLabs is one of the finest and best-rated hangover pills in the market today. You should consider purchasing a hangover supplement by MoreLabs for enhanced effectiveness and morning recovery.



Drinkwel is a hangover pill supplement that uses several vitamins, minerals, and herbal extracts to help support overall better functioning of your liver and processing toxins and aid in replenishing nutrients within your body. Apart from the standard Drinkwel supplement, the hangover supplements brand also offers several wellness formulas that target particular health and wellness goals. This supplement can also be known as a herbal hangover supplement. If you are someone who dwells on natural and organic ingredients, then Drinkwel may be the perfect choice for you.

This flagship Drinkwel formula comprises NAC, taurine, alpha-lipoic acid, milk thistle, green tea extract, L-theanine, DHM, among significant quantities of essential vitamins and minerals. It is regarded as a multivitamin as it provides numerous benefits to its users combined with a liver and detox formula. Drinkwel offers some of the most potent dosage options on our list of Best hangover supplements and contains some of the most proven ingredients compared to other supplements mentioned on this list. This option is why it continues to be the best hangover pill you can buy in 2021.



PureWine is the only hangover supplement on our list of Best Hangover Supplements for 2021 that works on physically removing hangover-causing compounds from your wine. Alcohol not only affects your brain but also has physical effects on your body. A bad hangover can further exacerbate these physical, painful effects. But you should not worry, as PureWine is here to help. The company’s hangover supplements strive to eliminate the biological effects of a hangover from your body. Unlike many popular hangover supplements, you should not take this hangover formula before or after a drink. Instead, you should use it while consuming a beverage for the best results. The hangover supplements created by PureWine use a patented Phoenix filtration system to get rid of sulfites and histamines from your wine. It is worth knowing that the headaches that you usually get after having your wine come from sulfites and histamines in your Drink which is precisely what PureWine hangover supplement targets to enable your overall well-being.

There is another significant advantage of using PureWine’s products, and that is that the company manufactures supplements that help remove oxidized components from your wine. Suppose you have had a situation where you did not store your wine under appropriate conditions or are trying to revive an old bottle of wine. In that case, PureWine can help remove any oxidized components from your wine, thereby enhancing its evergreen taste and flavor. To remove oxidation, PureWine is the best option there is. By now, you must have known that PureWine is a very niche product, but its Wine Purifier can do wonders and remove the same components from your wine that lead to hangovers in the first place. If you are a wine-lover and consume it regularly, then PureWine could be a fantastic option for you. PureWine offers two standard filters: The Ward (used to filter each glass) and The Wave (used to filter each bottle).



Next on our list is DrinkAde, a hangover supplement that supports your body’s ability to neutralize the toxins, therefore helping you rehydrate. This particular hangover beverage has more than just drinking purposes. You can also enhance your lifestyle and make it more active and body recovery after working out. If you have been drinking heavily, dealing with stress lately, or spending long hours working, then DrinkAde could just be the right choice for you.

DrinkAde is perhaps one of the most popular hangover pill brands that are available in the market today. You can easily find it hanging at store shops across the nation. DrinkAde comes in two particular varieties- including prevention (that is, a caffeine-free, limeade flavored preventive measure) and Boost (which is a hangover pill that uses Caffeine and other B Vitamins to replenish your body the day after you’ve had your Drink).

This hangover supplement is priced at around $4 to $5 per serving, depending upon the type of pack you purchase- whether that is a 6-pack, 12-pack, or 24-pack, which makes it come under more expensive options on our list of best hangover pills. However, DrinkAde continues to be the top preference for its users and one of the best hangover pills in the hangover supplements space.



Cheers is another hangover supplement on our list that offers three different hangover formulas with additional functionality. The hangover supplements company provides Restore (which is an after-alcohol aid), Hydrate (which is an Oral Rehydration solution), and Protect (which is a daily liver supplement). Cheers hangover supplements cost about $20 to $35 per bottle, and it is designed for use before you go to bed. Suppose you start consuming various Cheers hangover supplements. In that case, you can very easily support your body’s natural defense against hangovers, help with rehydration within your body and protect your liver, all while experiencing several other benefits. Cheers produce its supplements in the United States (US), and just like other supplements on our list, the hangover supplements company uses proven ingredients such as DHM (1,200 mg).

As of 2021, Cheers has sold over 14 million hangover supplements while also receiving a patent on its vitamin B2 mix. This statistic is something that we haven’t come across in any other companies mentioned on this list. For all of the reasons listed upwards and beyond, Cheers is on the top of our list of best hangover supplements you should consider buying in 2021. What’s worth noting is that the hangover company also offers the option of a monthly auto-ship, thereby enabling its users to purchase the supplements at an even lower price.

Over EZ


Over EZ is a natural hangover prevention vitamin that claims to prevent your hangovers even before they occur. The price range of this hangover vitamin starts from $20 (able to control eight hangovers per pill) to $144 (able to prevent about 72 hangovers). This hangover supplement uses natural ingredients to prevent you from experiencing the aftereffects of consuming alcohol.

According to the official website of Over EZ, we recommend that you take one Over EZ capsule for about 15 minutes before consuming your first Drink or even while having it. Over EZ just doesn’t claim to prevent your hangovers, but it can also help boost your overall immune system. At the same time, you drink and even hasten the breakdown of hangover-inducing toxins in your body, thereby allowing you to become alive and energized even if you’ve had several shots down. It would be worth noting that Over EZ is also one of the few hangover supplements on our list available online through Walmart, Amazon, and other major retailers.



The following hangover remedy on our list is called Blowfish that claims to make you feel human again. This hangover formula is backed by science, recognized by the FDA, and guarantees to make you feel better in just 15 minutes. Blowfish hangover supplement is available at affordable price ranges starting from $15 (for a starter pack) to $100 (for a Double Party Box), among other such options.

One of the striking features of taking a Blowfish hangover supplement is that you consume it while you’re hungover. A vast majority of the hangover supplements listed here claim to prevent your hangover from even occurring, i.e., they recommend you take the supplement before consuming your Drink. However, Blowfish provides you with a morning hangover remedy that freshens up your entire day. The hangover supplements company also has a hangover-free guarantee and uses an effervescent tablet to make you feel alive and human again. It will work wonders for you even if you forgot to pop in a hangover pill the night before; Blowfish’s supplements got you covered.

The Plug


The Plug is a dietary supplement that uses natural ingredients to manufacture hangover pills to increase your overall productivity levels and replenish your body with essential nutrients to maintain hydration within your system. This plant-based formula uses 13 herbs, plants, fruits, and flowers, all blended with bedrock water to help you lead and become the most excellent version of yourself.

Hangover supplements made by The Plug are available across the United States at all convenience stores. The plant-based company also continues to expand its product rollout throughout the nation.

The Plug is best-known as the official partner of the UFC, and it contains ingredients such as purslane, Schisandra, dandelion, licorice root, honeysuckle flower, oriental raisin tree (DHM), mixed with other familiar and unique ingredients.

The Plug hangover supplement only contains 25 calories per serving without any added sugar or Caffeine. With its growing popularity, The Plug has emerged to be one of the top-rated hangover pills.



Zaca is another dietary supplement on our list that comes in the form of chewable tablets. This hangover supplement claims to support your hydration levels and liver functioning, and we recommend that you take two of Zaca’s chewable tablets at a time to combat bad hangovers and dehydration. Just like other hangover pills on this list of Best hangover supplements, Zaca markets itself as a general recovery aid; this means that you can use it as both pre and post-workout formulas. This solution will strengthen you to fight the aftereffects of overheating, traveling, and altitude, or whenever you’re feeling a little ‘meh,’ amongst its many other uses.

As a hangover supplement, Zaca contains Japanese raisin, L-glutamine, L-glutathione, and prickly pear. This hangover pill contains proven ingredients to help support your liver and hydration while providing you with essential nutrients and elements that you may require to fight the drinking aftereffects. Zaca works pretty similarly to other hangover supplements mentioned on this list of best hangover supplements that contain amino acids, antioxidants, herbs, and plants that aid your liver and boost hydration levels within your body.



The next hangover supplement brand on our list is called NoDaysWasted. This hangover supplements company has been promoting itself all across the Internet recently. NoDaysWasted works quite similar to other hangover supplements companies on our list. It comes packaged with proven ingredients such as DHM and helps fight the toxins off of your body created during alcohol consumption. You may also note that when you’re indulging in drinking, your body produces toxins like acetaldehyde, and science has proven that the presence of DHM helps fight this particular toxin from your body.

NoDaysWasted is a plant-based formula that uses DHM, L-cysteine, milk thistle, organic prickly pear, B vitamins, sodium, potassium, among other similar ingredients. We recommend that you take one packet (which contains two capsules) of this hangover formula during your night out with a glass of water or one before going to bed. For nights where you’ve had heavy doses of drinking, it would be helpful to take more than just one packet, depending upon your requirements, of course. NoDaysWasted costs $34 for a pack of ten, and it falls under one of the reasonably priced formulas on our list.



The next hangover supplement brand on our list is Toast that offers a line of berry-flavored gummies to help you deal with the effects of a hangover. Toast gummies are the latest science-backed hangover supplement that uses ingredients such as milk thistle and matcha to fight the drinking aftereffects. Toast comes packaged in a pocket-size pouch that contains two servings per packet. This mobility makes the gummies come in handy and therefore easy to consume while on the go. We recommend that the hangover supplement brand take one serving (with about five gummies) before drinking alcohol and one additional serving (containing five gummies) if required on heavy drinking nights.

The hangover supplement- Toast, is priced at $30 for a total of 12 servings which makes it another reasonably-priced hangover supplement on our list of best hangover supplements that you should consider buying in 2021. Toast offers the option of $2.50 per serving for people who do not want to spend $6 to $10 on a hangover supplement. Toast founded its pre-drinking gummies on a firm belief- constantly raising a toast to your health before drinking, and that is precisely where the name- ‘Toast’ was derived.

LiquidIV Energy Multiplier


LiquidIV’s Energy Multiplier is an energy supplement that boosts your energy levels using its proven ingredients. The right way to go about consuming this energy drink is that you mix one packet of Energy Multiplier’s powder with water and then drink it to help quickly support your body after a hangover.

While this energy drink doesn’t specifically market itself as a hangover supplement or hangover pill, LiquidIV’s Energy Multiplier has become a popular choice among people looking to boost their hydration and energy levels post-drinking. If you are looking to fill your body with natural goodness, rejuvenation, and energy boost first thing in the morning, then this Energy Multiplier could be the right choice for you. Each serving of LiquidIV’s Energy Multiplier contains approximately 100 g of Caffeine and other proven energy booster ingredients like matcha, guayusa, and ginger, among others.

LiquidIV’s Energy Multiplier will ensure that you stay productive even the day after you’ve drunk heavily by providing your body with antioxidants, Caffeine, and other essential sources of energy. On this specific list of Best hangover supplements, LiquidIV’s Energy Multiplier is one of the most affordable options available for you at just $25 per package (which means a total of 14 servings per packet).

Purple Tree


As per the official website of Purple Tree, the company describes its products as “Celebration Vitamin” pills. This hangover solution can either be bought as hydration drops or as capsules. You can boost your hydration levels and avoid the effects of a hangover by adding Purple Tree’s hydration drops (which are in liquid form) to 16oz of water. You may also note that the Purple Tree capsules contain similar ingredients as their hydration drops.

Once you start taking Purple Tree’s hangover supplements, you can purportedly support healthy liver functioning, replenish essential vitamins and electrolytes lost while drinking, and help you to enjoy your mornings to the fullest without falling into the trap of unproductivity. As advertised by the hangover supplement company itself, Purple Tree claims its products to be the world’s purest form of electrolyte drink blend. This potency enables the brand to provide your body with 100% pure mineral salts, essential trace elements, and other fast-acting electrolytes without sugar. Different hangover hydration formulas almost always contain sugar.

The price range of the San Diego-based company’s hangover products ranges from $15 to $35 per bottle.



Sobur is a hangover support pill that promises that you would never have to go through a hangover again after its consumption. Sobur provides your brain and body the protection you seek after consuming alcohol while also putting a substantial full stop to your hangovers and helping you feel refreshed and wake up to energized mornings.

To provide your body with all of these benefits and more, Sobur uses several similar ingredients as with other hangover supplements mentioned on our list, like DHM, Vitamin C, B Vitamins, N-acetyl L-carnitine, among other proven ingredients. When mixed to formulate a perfect blend of energy and hydration, all of these ingredients helps you to fight the causes of your hangover, including toxins like acetaldehyde. This hangover formula also claims to target your low blood sugar levels, dehydration, amongst other aftereffects of drinking alcohol. This hangover supplement costs just $35 for a total of 10 servings (which equals 20 capsules). It has emerged as a popular and competitively-priced (falling in mid-range options) hangover supplement on our list.

Fewer Regrets


Fewer Regrets comes across as the Ultimate Hangover Prevention formula that stands by its brand name and helps live your life with fewer regrets. However, you must note that the hangover supplement company doesn’t claim to remove all regrets from your life; it just strives to reduce your number of guilt and make them few. Fewer Regrets uses a total of eight natural ingredients in its hangover supplement blend to help you combat the aftereffects of hangovers. This supplement costs about $50 for about 12 servings.

Fewer Regrets products contain green tea extract, Hovenia Dulcis, milk thistle, prickly pear cactus, turmeric extract, among other proven ingredients. Some of these components are known to have antioxidant effects. At the same time, these ingredients can boost your overall liver performance and functioning. The Price of this supplement is a bit expensive for a mid-range supplement option, especially when we compare it to other hangover products on our list. However, Fewer Regrets stand out from its competitors by using an antioxidant formula that is effective enough to fight your hangover after effects. This reason is why we think it would be a good fit for you if you don’t mind going a little pricey at times.

How We Ranked the Best Hangover Supplements

Every hangover supplement that is available in the market today claims to stop or prevent your hangovers. But, only a few can live up to that standard. Some of the best hangover pills you consume can turn your life around by making you feel more energetic, refreshed, and hydrated. But, now more than ever, there’s a solid need to be able to separate the worst from the best. So, we have done the work for you. Based on the following metrics, we split the good hangover supplements from artificial or filtered hangover supplements. These metrics are:

Proven Ingredients

Hangovers have been here for as long as civilization. Some of these hangover remedies are decades old, and therefore people do not shy away from trusting these well-established brands. However, other hangover cures use science to complement their overall ingredients mix. However, for this particular list of the best hangover supplements that you should consider buying in 2021, we only preferred hangover pills that used proven ingredients and offered effective dosage options to their users.


Another critical factor that we considered while compiling this list for the best hangover supplements was checking whether a particular hangover formula was science-backed or not. It is tough to monitor and even scientifically test hangover pills in a controlled environment, and we are well aware that alcohol affects different people differently. However, some of the best hangover supplements companies have cited clinical trials to prove that their hangover remedy pills work as advertised and directed to help cure your hangovers. You should note that for this particular list, we looked favorably upon hangover supplements that underwent clinical trials, had extensive reference pages, among other similar factors.

Manufacturer Reputation and Transparency

To be well-known and established, some hangover supplements companies have been out in the hangover remedy market for a long time. These popular hangover supplements brands are often known for creating good-quality products. Some of these also have their medical advisory boards to avoid any clinical discrepancies. While making this list for ranking the best hangover supplements in 2021, we considered the manufacturer’s reputation and the transparency in their formulas.

Price and Value

The Price of a hangover supplement was as important to us while ranking as the value that a particular hangover supplement provided its customers. It is not unusual that some people are open to spending up to $50 and more on purchasing hangover supplements that will cure their bad headaches and other aftereffects of drinking. However, other people would want a hangover pill not more than $5. So, it was essential for us to feature and accommodate the price ranges according to different individual needs. So, we made it clear to include different price ranges for the best hangover supplements in our list. However, we only considered hangover products that delivered the maximum value at the said Price for the users so that not even a penny from their pocket goes to waste.

Easy Usage

Some of the best hangover pills also come packaged with an easy-to-use formula that allows the users to quickly and conveniently take a hangover pill to cure the alcohol aftereffects. Most hangover remedies come with an easy-to-use interface to ensure smooth functioning for their users. It can be as straightforward as just taking a pill or a capsule to enjoy the benefits of its ingredients. Some hangover supplements require a thorough mix with water before consumption. However, for this specific list of the best hangover supplements, we preferred the ones that supported an easy-to-take way and were handy, enabling users to consume them while on the go.

Money-Back Guarantee

Different people consume alcohol for various purposes. People will process alcohol consumption in different ways. Some people can prevent their hangovers with a simple B vitamin supplement, while others often require herbal extracts, adaptogens, and other inflammatory plant extracts to overcome the side effects. However, some of the top-rated hangover pills come with a Money back guarantee for their users. This feature assures the people that they are not getting cheated on and allows them to get a cashback if, for some reason, they were unsatisfied with a particular hangover supplement product. For this specific list of best hangover supplements, we preferred hangover supplements that backed up their products’ benefits claims with some form of satisfaction or money-back guarantee for the customers.

Some Common Side Effects of Hangover Supplements

It may come to you as a form of relief that most hangover supplements manufactured these days are healthy for normal adults when used in recommended dosages with no side effects.

After all, the whole point of a hangover pill existing and supporting you on your drinking journey is to help prevent hangovers from taking place by combating the side effects of drinking and promoting liver health and hydration levels within your body.

However, as different people have different needs and no one person is similar, our bodies respond differently to the same ingredients. Our processing powers and abilities are quite different from those around us, which is why it’s not uncommon to find that some of you may be allergic to some of the ingredients present in these hangover supplements, including herbal or plant-based extracts. Naturally, some of you may respond differently to these ingredients and, as a result, may develop an allergic reaction towards certain specific elements, which varies from one person to another.

Some of you may even experience some form of digestive discomfort after consuming these hangover pills for the first time or if you end up exceeding the dosage limit for a particular supplement.

But typically, under general conditions, if you are a healthy human being, you can expect almost no side effects from consuming a hangover remedy or hangover supplement. If you are still unsure of whether you should consume a hangover supplement or not, then we recommend you consult your family or personal doctor for specific and targeted advice.

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Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.